<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TJC2436148 TJC2436148 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, T215TNSY   G190S, M230ML   V35T, T39EK, S48T, K122E, D123N, K173T, T200A, Q207E, R211K, L228LQ, V245K, E248D, D250E, A272P, K277R, Q278N, T286A, V292I, I293V  
>TJC2436148| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICKEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPDIVI
YQYVDDLYVSSDLEIGQHRAKIEELREHLLKWGFYTPDKKHQKEPPFQWLGYELHPDKWT
VQPIKLPDKESWTVNDIQKLVGKLNWASQIYPGIKVRNLCKLLRGAKALTEIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, G16E, L19I, M36I, L63A, H69K, T74S, L89M, I93L  
>TJC2436148| codons 1-99
PQITLWQRPLVSIKVEGQIKEALLDTGADDTVLEEINLPGRWKPKMIGGIGGFIKVRQYD
QIAIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009