<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
2360507 2360507 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   V106M V179D V35T, E36EA, T39E, K102KR, K103R, D123S, I135L, D177E, Q207E, R211K, F214L, V245Q, A272P, K277R, E291D, V292I, I293V, P294T, E308EK, I309IV, L310X P157PR
>2360507| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKRRKSMTVLDVGDAYFSVPL
DKSFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSRAIFQSSMTKILEPFRKQNPEIDI
YQYVDDLYVGSDLEIGQHRTKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIVTLTEEAE
LELAENRKVXKEPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, E34EK, M36MI, R41K, D60E, L63P, H69K, T74TA, V75VI, L89M, I93L  
>2360507| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLKEINLPGKWKPKMIGGIGGFIKVRQYE
QIPIEICGKKAIGAILVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009