<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TJC2422791 TJC2422791 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
K65R, Y115F   K101E, V106M F227FL V21I, V35T, T39EK, S48T, V60I, D123E, T139TK, S162C, K173A, Q174R, D177E, I178L, I195M, T200A, Q207E, V245Q, A272P, K277T, K281R, E291D, V292I, I293V G231GR
>TJC2422791| codons 1-333
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICKEMEKEGKITKIGPENPYNTPI
FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSMTVLDVGDAFFSVPL
DKEFRKYTAFTIPSINNEKPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRARNPELVI
YQYMDDLYVGSDLEMGQHRAKIEELREHLLRWGFTTPDKKHQKEPPLLWMRYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVTQLCRLLRGTKALTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, L63T, H69K, I93L  
>TJC2422791| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QITIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009