Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TJC2422791 | TJC2422791 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, Y115F | K101E, V106M | F227FL | V21I, V35T, T39EK, S48T, V60I, D123E, T139TK, S162C, K173A, Q174R, D177E, I178L, I195M, T200A, Q207E, V245Q, A272P, K277T, K281R, E291D, V292I, I293V | G231GR |
| >TJC2422791| codons 1-333 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICKEMEKEGKITKIGPENPYNTPI FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSMTVLDVGDAFFSVPL DKEFRKYTAFTIPSINNEKPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRARNPELVI YQYMDDLYVGSDLEMGQHRAKIEELREHLLRWGFTTPDKKHQKEPPLLWMRYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVTQLCRLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, L63T, H69K, I93L |
| >TJC2422791| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QITIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |