<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
GT00131322 GT00131322 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, K14R, I15V, L19T, M36I, N37NS, L63T, H69K, V82I, L89M, I93L  
>GT00131322| codons 1-99
PQITLWQRPLVSIRVGGQTKEALLDTGADDTVLEEISLPGRWKPKMIGGIGGFIKVRQYD
QITIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, V75T, M184V, T215F A62V K103N, M230L   K20KR, V35T, T39E, S48T, S68SG, K101KR, K102Q, K122E, D123G, K173A, Q174K, D177E, T200A, Q207E, R211K, H221L, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V, I309V, L310F, I329L  
>GT00131322| codons 1-333
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEELEKEGKITKIGPENPYNTPV
FVIKKKDGTKWRKLTDFRELNKRTQDFWEVQLGIPHPAGLRQNKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGFFTPDKKLQKEPPFLWLGYELHPDKWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREVFKEPVHGVYYDPSKDLIAELQKQG

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009