Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TJC2473909 | TJC2473909 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | A62AV | K103N | A98G | V35T, E36A, T39E, S48T, V106I, K122E, D123N, I135T, T139A, Q174E, P176Q, D177E, T200A, I202V, Q207E, F214L, E248ED, D250E, S251D, A272P, T286A, E291D, V292I, I293V | N175T |
| >TJC2473909| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FVIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKNKSITVLDVGDAYFSVPL DENFRKYTAFTIPSTNNEAPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKETQEIVI YQYVDDLYVGSDLEIGQHRAKVEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPDKEDWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I13V, I15V, L19I, M36I, R41K, D60E, Q61E, L63P, H69K, L89M, I93L |
| >TJC2473909| codons 1-99 PQITLWQRPLVSVKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE EIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |