<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TJC2385322 TJC2385322 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V, L210W   K103N K238N V35T, E36A, T39E, E40D, S48T, K104R, V118I, K122E, D123S, E138A, T139A, I142IT, T165L, K173T, Q174K, Q197K, T200A, I202V, Q207E, R211K, F214L, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E308K, I309V, L310C, P313Q, V317A  
>TJC2385322| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEDMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNRSVTVLDVGDAYFSIPL
DESFRKYTAFTIPSINNAAPGTRYQYNVLPQGWKGSPAIFQSSMLKILEPFRTKNPDIVI
YQYVDDLYVGSDLEIGKHRAKVEELREHLWKWGLTTPDKKHQKEPPFLWMGYELHPDNWT
VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAENRKVCKEQVHGAYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12P, I13V, I15V, L19I, E35D, M36I, R41K, D60K, Q61E, L63P, H69K, V82I, L89M, I93L Q58H, Y59M
>TJC2385322| codons 1-99
PQITLWQRPLVPVKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRHMK
EIPIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009