Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TJC2385322 | TJC2385322 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12P, I13V, I15V, L19I, E35D, M36I, R41K, D60K, Q61E, L63P, H69K, V82I, L89M, I93L | Q58H, Y59M |
| >TJC2385322| codons 1-99 PQITLWQRPLVPVKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRHMK EIPIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, L210W | K103N | K238N | V35T, E36A, T39E, E40D, S48T, K104R, V118I, K122E, D123S, E138A, T139A, I142IT, T165L, K173T, Q174K, Q197K, T200A, I202V, Q207E, R211K, F214L, V245Q, E248D, A272P, T286A, E291D, V292I, I293V, E308K, I309V, L310C, P313Q, V317A |
| >TJC2385322| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEDMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNRSVTVLDVGDAYFSIPL DESFRKYTAFTIPSINNAAPGTRYQYNVLPQGWKGSPAIFQSSMLKILEPFRTKNPDIVI YQYVDDLYVGSDLEIGKHRAKVEELREHLWKWGLTTPDKKHQKEPPFLWMGYELHPDNWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENRKVCKEQVHGAYYDPSKDLIAEIQKQG |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |