<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TJC2413549 TJC2413549 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K101E, G190A V179DE, P225H E28EGKR, V35M, E36A, T39E, E40D, S48T, K103R, K122E, D123S, S162C, K173T, T200A, Q207D, R211K, V245Q, D250DE, A272P, Q278CNSY, K281R, E291D, V292I, I293V, L310CF, Q334N E138N
>TJC2413549| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTREKIKALMAICEDMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKRKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNNTPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRTQNPDIEI
YQYVDDLYVASDLEIGQHRAKIEELRDHLLKWGFTTPDKKHQKEHPFLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKYLCRLLRGTKALTDIVPLTEEAE
LELAENREIFKEPVHGVYYDPSKDLIAEIQKQGNG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, N37D, R41K, I62IV, L63C, H69K, A71T, I93L  
>TJC2413549| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEIDLPGKWKPKMIGGIGGFIKVRQYD
QVCIEICGKKTIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009