Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 2360434 | 2360434 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K101KE, K103KN | V21VI, V35T, E36A, T39D, W88S, V118I, K122E, D123N, I135V, E138A, I142IT, E169Q, K173T, Q174K, T200A, K201KR, I202V, Q207K, R211K, F214L, P243T, V245Q, A272P, K275R, Q278N, T286A, E291D, V292I, I329V |
| >2360434| codons 1-334 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTAICDEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFSEVQLGIPHPAGLEKNKSVTVLDVGDAYFSIPL DENFRKYTAFTIPSVNNATPGTRYQYNVLPQGWKGSPAIFQSSMTKILQPFRTKNPDIVI YQYVDDLYVGSDLEIGQHRARVEELRKHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQTIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKNLCKLLRGAKALTDIIPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEVQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, E35D, M36I, R57RK, D60E, L63P, H69K, V82VI, L89M, I93L |
| >2360434| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDINLPGRWKPKMIGGIGGFIKVKQYE QIPIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |