Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 2344227 | 2344227 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, M184V | K103N, V106M | V35T, E36A, T39DE, S48T, V60I, I94IL, K122E, D123S, I132L, K166R, K173I, Q174K, T200A, I202IV, Q207E, F214L, V245E, K277R, T286A, E291D, V292I, I293V, E308EK, I309IV |
| >2344227| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI FAIKRKDSTKWRKLVDFRELNKRTQDFWEVQLGLPHPAGLKKNKSMTVLDVGDAYFSVPL DESFRKYTAFTLPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRIKNPDIVI YQYVDDLYVGSDLEIGQHRAKVEELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENRKVLKEPVHGVYYDPSKDLIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, E35D, M36I, R41K, H69K, T74S, L89M, I93L |
| >2344227| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |