Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TJC2368272 | TJC2368272 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, M184V | K101E, G190E | E138K | K20R, E28G, V35T, T39E, S48T, K122E, D123S, Q174K, V179G, G196E, T200A, E203K, Q207E, R211K, V245Q, A272S, K275Q, K277R, T286A, E291D, V292I, I293V, P294T, I329V, Q334N |
| >TJC2368272| codons 1-335 PISPIETVPVKLKPGMDGPRVKQWPLTGEKIKALTEICEEMEKEGKITKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSINNKTPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKKNPDIGI YQYVDDLYVESDLEIEQHRAKIKELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIQVRQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEVQKQGNG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, N37S, R41K, D60E, Q61E, L63P, H69K, K70R, I93L |
| >TJC2368272| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYE EIPIEICGKRAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |