Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TJC2389852 | TJC2389852 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K219E | K103KN, V106VIM, Y188C | A98G, V108VI | V35T, E36A, T39E, K122E, D123GS, K173A, Q174K, D177E, T200A, E203ED, Q207E, R211K, F214L, V245Q, A272P, K277R, V292I, I293V, I309V, L310X, I329L |
| >TJC2389852| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKNKSMTILDVGDAYFSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYVDDLCVGSDLEIGQHRAKIDELREHLLKWGLTTPDEKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTEIVPLTEEAE LELAENREVXKEPVHGVYYDPSKDLIAELQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14R, I15V, Q18E, L19V, K20R, E35D, N37D, H69K, V77I, L89M, I93L |
| >TJC2389852| codons 1-99 PQITLWQRPLVTIRVGGEVREALLDTGADDTVLEDMDLPGRWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |