<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TJC2414872 TJC2414872 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67N, K70E, M184V   V106M F227L V35T, E36A, T39E, E40K, S48T, K122E, D123N, I135M, S162D, K173T, I178M, V179VI, T200A, E204K, Q207E, R211K, F214L, H221Y, V245L, A272P, K275Q, V276I, K281R, L283I, T286A, E291D, V292I, I293V, P294Q, L310I, Q334H  
>TJC2414872| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEKMEKEGKITKIGPENPYNTPV
FAIKKKNSTEWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL
DENFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQDSMTKILEPFRTQNPDMII
YQYVDDLYVGSDLEIGQHRAKIEKLREHLLKWGLTTPDKKYQKEPPLLWMGYELHPDKWT
VQPILLPEKDSWTVNDIQKLVGKLNWASQIYPGIQIKQLCRLIRGAKALTDIVQLTEEAE
LELAENREIIKEPVHGVYYDPSKDLIAEIQKQGHG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, D60E, L63T, H69K, L89M, I93L  
>TJC2414872| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE
QITIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009