Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TJC2371553 | TJC2371553 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M, M184V | F116Y | K103N | P225H | V8I, V35T, E36A, T39E, S48T, V60I, S68G, K122E, D123G, K173A, Q174K, D177E, I178IM, G196E, T200A, Q207E, R211K, V245Q, A272P, E291D, V292I, I293V, D324E |
| >TJC2371553| codons 1-333 PISPIETIPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI FAIKKKDGTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYYSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRAKNPEMVI YQYVDDLYVGSDLEIEQHRAKIEELREHLLKWGFTTPDKKHQKEHPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKELIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, K20R, M36I, R41K, R57K, L63V, H69K, L89M, I93L |
| >TJC2371553| codons 1-99 PQITLWQRPLVSIKVGGQIREALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVKQYD QIVIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |