Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 2346440 | 2346440 | South Africa | 2008 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, E35D, M36I, R41K, D60E, H69K, L89I, I93L |
| >2346440| codons 1-99 PQITLWQRPLVSIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYE QILIEICGKKAIGTVLVGPTPVNIIGRNILTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K65R, Q151M, M184V | V75I, F116Y | K101E, G190A | F227L | V35T, T39E, S48T, V60I, S68G, V118I, K122E, D123S, I132L, E138A, T139A, K173T, Q174K, D177E, V179I, T200A, I202V, E204D, Q207E, R211K, F214L, V245Q, A272S, T286A, E291D, V292I, I293V, V317A, I329L |
| >2346440| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPENPYNTPI FAIKRKDGTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLEKKKSVTVLDVGDAYYSIPL DESFRKYTAFTLPSINNAAPGIRYQYNVLPMGWKGSPAIFQSSMTKILEPFRTKNPEIII YQYVDDLYVASDLEIGQHRAKVEDLREHLLKWGLTTPDKKHQKEPPLLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGAYYDPSKDLIAELQKQGQG |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |