Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| AACS7925A | AACS7925A | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K219E | K103N, Y188H | K20R, V35T, E36A, T39E, E40D, V60I, D121H, K122E, K173RT, Q174K, D177E, I178L, G196E, T200A, Q207E, L228H, V245E, D250DE, S251SCG, A272P, K277KR, T286A, E291D, V292I |
| >AACS7925A| codons 1-333 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTAICEDMEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPELVI YQYVDDLHVGSDLEIEQHRAKIEELREHLLRWGFTTPDEKHQKEPPFHWMGYELHPDKWT VQPIELPEKEGWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIIPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19V, M36I, R41K, H69K, T74S, L89M, I93L |
| >AACS7925A| codons 1-99 PQITLWQRPLVTIKVGGQVKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGSVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |