Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 2363278 | 2363278 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N | T27S, V35T, E36A, T39E, S48T, K122KE, K173T, D177E, T200A, E204K, Q207D, R211K, V245Q, D250DE, A272P, K277R, T286TA, E291D, V292I, I293V |
| >2363278| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLSEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEKLRDHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| Q58E | I15V, L19I, E35D, M36I, P39PS, R41K, D60E, Q61E, L63P, H69K, L89M, I93L |
| >2363278| codons 1-99 PQITLWQRPLVTIKVGGQIKEALLDTGADDTVLEDINLSGKWKPKMIGGIGGFIKVREYE EIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |