<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TJC2395299 TJC2395299 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V V75VI K103KN, V106M F227L T27S, V35T, T39K, V60I, D121Y, K122E, I132IL, I135T, S162C, K173A, Q174K, D177E, I178L, T200A, Q207E, V245Q, A272P, Q278H, L279M, K281R, T286A, E291D, I293V, Q334N  
>TJC2395299| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLSEEKIKALTEICKEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLKKNKSMTVLDVGDAYFSVPL
YEDFRKYTAFTLPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRAKNPELVI
YQYVDDLYVGSDLEIGQHRAKIEELREHLLRWGFTTPDKKHQKEPPLLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKHMCRLLRGAKALTDVVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQGNG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19T, K20R, M36I, N37T, R41K, Q61E, L63CPRS, H69K, L89M, I93L  
>TJC2395299| codons 1-99
PQITLWQRPLVSIKVGGQTREALLDTGADDTVLEEITLPGKWKPKMIGGIGGFIKVRQYD
EISIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009