<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
GT00057847 GT00057847 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V A62V K101E, G190V   V35T, E36A, T39E, S48T, T58S, V90I, K122E, D123S, I135IT, N147NK, K173A, Q174K, D177E, T200A, E203G, Q207E, R211K, V245Q, K277R, T286A, E291D, V292I, I293V, E297K  
>GT00057847| codons 1-314
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNSPV
FVIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLEKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYKVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI
YQYVDDLYVVSDLEIGQHRAKIGELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGAKALTDIVPLTKEAE
LELAENREILKEPV

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L19I, M36I, R41K, L63P, H69K, I93L  
>GT00057847| codons 1-99
PQITLWQRPLVTIKIGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009