<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TJC2384408 TJC2384408 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+EFV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, M184V, L210W, T215Y V75M, F77L, K219KQ V106M, G190A K101H, F227L V35I, E36A, T39E, S48T, T69N, K122E, D123N, I135T, K173T, T200A, Q207E, R211K, F214FL, A272P, K275Q, K277R, T286A, A288T, E291D, V292I, I293V  
>TJC2384408| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALIAICEELEKEGKITKIGPENPYNTPV
FAIKKKNSNRWRKLMDLRELNKRTQDFWEVQLGIPHPAGLHKKKSMTVLDVGDAYFSVPL
DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPDIVI
YQYVDDLYVASDLEIGQHRAKIEELREHLWKWGLYTPDQKHQKEPPLLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIQVRQLCKLLRGAKTLTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, E35D, M36MI, N37ND, R41K, D60E, L63P, H69K, V77VIM, I93L  
>TJC2384408| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYE
QIPIEICGKKAIGTVLMGPTPVNIIGRNLLTQLGCTLNF

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009