Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TJC2399847 | TJC2399847 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V, T215Y | V75I | Y181C | V35T, T39E, S48T, E53D, K122E, D123S, I132L, K173T, T200E, E204Q, Q207E, R211K, H221Y, V245Q, A272P, K277R, Q278H, T286A, E291D, V292I, I293V, I309IV |
| >TJC2399847| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEEMEKEGKITKIGPDNPYNTPV FAIKKKDSTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTLPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPDIVI CQYVDDLYVGSDLEIGQHREKIEQLREHLLKWGFYTPDKKYQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRHLCKLLRGAKALTDIVPLTEEAE LELAENREVLKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, G16E, L19I, R41K, Q61E, L63A, H69K, I72T, T74S, V77I, L89M, I93L |
| >TJC2399847| codons 1-99 PQITLWQRPLVSIKVEGQIKEALLDTGADDTVLEEMNLPGKWKPKMIGGIGGFIKVRQYD EIAIEICGKKATGSVLIGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |