Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TJC2394973 | TJC2394973 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V106M, M230L | V179D | E6K, K11N, K32R, V35T, T39E, S48T, W88S, K103R, K122E, D123N, E138A, K173T, Q174K, T200A, I202V, E204Q, Q207E, R211K, F214L, V245Q, E248D, D250A, A272P, K275R, Q278H, K281R, T286A, A288T, E291D, V292I, I293V, I329L, Q334E |
| >TJC2394973| codons 1-334 PISPIKTVPVNLKPGMDGPKVKQWPLTEEKIRALTEICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFSEVQLGIPHPAGLKKRKSMTVLDVGDAYFSVPL DENFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDIDI YQYVDDLYVGSDLEIGQHRAKVEQLREHLLKWGLTTPDKKHQKEPPFLWLGYELHPDKWT VQPIQLPDKASWTVNDIQKLVGKLNWASQIYPGIRVKHLCRLLRGAKTLTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAELQKQGE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14R, I15V, L19I, K20R, E35D, M36L, N37E, R41K, D60E, H69K, V82I, L89M, I93L |
| >TJC2394973| codons 1-99 PQITLWQRPLVTIRVGGQIREALLDTGADDTVLEDLELPGKWKPKMIGGIGGFIKVRQYE QILIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |