<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
TJC2394973 TJC2394973 South Africa 2008 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+D4T+EFV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    K14R, I15V, L19I, K20R, E35D, M36L, N37E, R41K, D60E, H69K, V82I, L89M, I93L  
>TJC2394973| codons 1-99
PQITLWQRPLVTIRVGGQIREALLDTGADDTVLEDLELPGKWKPKMIGGIGGFIKVRQYE
QILIEICGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   V106M, M230L V179D E6K, K11N, K32R, V35T, T39E, S48T, W88S, K103R, K122E, D123N, E138A, K173T, Q174K, T200A, I202V, E204Q, Q207E, R211K, F214L, V245Q, E248D, D250A, A272P, K275R, Q278H, K281R, T286A, A288T, E291D, V292I, I293V, I329L, Q334E  
>TJC2394973| codons 1-334
PISPIKTVPVNLKPGMDGPKVKQWPLTEEKIRALTEICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFSEVQLGIPHPAGLKKRKSMTVLDVGDAYFSVPL
DENFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDIDI
YQYVDDLYVGSDLEIGQHRAKVEQLREHLLKWGLTTPDKKHQKEPPFLWLGYELHPDKWT
VQPIQLPDKASWTVNDIQKLVGKLNWASQIYPGIRVKHLCRLLRGAKTLTDIVPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAELQKQGE

References
Author Title Citation
Wallis, CL Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. JAIDS, 2009