Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TJC2381559 | TJC2381559 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N, Y188HL | V108VI | P4S, V35T, E36A, T39E, S48T, K122E, D123E, S162A, K173T, G196GR, Q197E, T200A, Q207E, R211K, V245Q, A272P, K277R, L283I, E291D, V292I, I293V, E308K, I309V, L310C |
| >TJC2381559| codons 1-333 PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTILDVGDAYFSVPL DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTQNPDIVI YQYVDDLLVGSDLEIREHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLIRGTKALTDIVPLTEEAE LELAENRKVCKEPVHGVYYDPSKDLIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L19I, M36I, R41K, Q61D, L63T, I64L, H69K, L89M, I93L |
| >TJC2381559| codons 1-99 PQITLWQRPLVTIKIGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD DITLEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |