Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| TJC2382730 | TJC2382730 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NVP | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103N | V35T, E36A, T39E, S48T, V60I, V118I, K122S, I135T, E138A, K173T, Q174K, I178L, T200A, Q207E, R211K, F214L, V245Q, E248D, D250DG, A272P, K275R, Q278H, T286A, E291D, V292I, I293V, E297A, K311R, I329V |
| >TJC2382730| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSIPL DSDFRKYTAFTIPSTNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDLVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKGSWTVNDIQKLVGKLNWASQIYPGIRVKHLCKLLRGAKALTDIVPLTAEAE LELAENREILREPVHGVYYDPSKDLIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, G16E, L19T, E35D, M36I, R41K, K45R, R57K, D60E, L63T, H69K, I93L |
| >TJC2382730| codons 1-99 PQITLWQRPLVTIKVEGQTKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYE QITIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |