Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 2280393 | 2280393 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V106M | V179E | K20R, V35T, T39E, S48T, K49R, V60I, E138A, T139I, K173T, Q174K, T200A, I202IV, Q207E, R211K, F214L, V245Q, E248D, A272P, E291D, V292I, I293V, P321T, D324E, I326IM |
| >2280393| codons 1-333 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALTEICEEMEKEGKITRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSMTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNAIPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDIEI YQYVDDLYVGSDLEIGQHRAKVEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDTSKELMAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19T, K20R, E35D, M36I, N37D, R41K, R57K, D60E, H69K, L89M, I93L |
| >2280393| codons 1-99 PQITLWQRPLVSIKVGGQTREALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVKQYE QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |