Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| GT00376922 | GT00376922 | South Africa | 2008 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+EFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, T215Y | K103N | K20R, V35M, T39D, I135M, K173A, D177E, T200A, Q207D, R211K, V245Q, D250E, A272P, K277R, T286A, E291D, V292I, E312Q |
| >GT00376922| codons 1-320 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMEICDELEKEGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSMNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRDHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIIPLTEEAE LELAENREILKQPVHGVYYD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19T, K20R, M36I, R41K, K43KR, L63P, H69K, V77I, L89LM, I93L |
| >GT00376922| codons 1-99 PQITLWQRPLVSIKVGGQTREALLDTGADDTVLEEINLPGKWRPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLIGPTPVNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Wallis, CL | Varied HIV drug resistance patterns among patients on failing antiretroviral therapy in the South African national roll-out programme. | JAIDS, 2009 |