Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| V2000-14 | V2000-14P | Italy | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 60 |
| 2 | AZT+DDI | 52 |
| 3 | 3TC+D4T+RTV | 8 |
| 4 | 3TC+D4T+IDV | 12 |
| 5 | 3TC+D4T+SQV | 20 |
| 6 | 3TC+D4T+RTV+SQV | 12 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K219Q | V60I, T69N, K103R, N175K, G196E, Q197K, Q207E, R211K, F214L, D218E | D113E, I159R |
| >V2000-14P| codons 30-226 KIKALVEICTEMEKEGKISKIGPENPYNTPIFAIKKKNSNRWRKLVDFRELNKRTQDFWE VQLGIPHPAGLKKRKSVTVLDVGEAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVL PQGWKGSPARFQSSMTKILEPFRKQKPDIVIYQYVDDLYVGSDLEIEKHRTKIEELREHL LKWGLTTPEQKHQKEPP |
References
| Author | Title | Citation |
| Venturi, G | Antiretroviral resistance mutations in human immunodeficiency virus type 1 reverse transcriptase and protease from paired cerebrospinal fluid and plasma samples. | J Infect Dis, 2000 |
| Gonzales, MJ | Protease and reverse transcriptase mutation patterns in HIV-1 isolates from heavily treated persons: comparison of isolates from northern California with isolates from other regions. | ARHR, 2003 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |