<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
DG446 DG446 Cameroon 2007 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, G17E, K20I, E35K, M36I, R41K, H69K, L89M  
>DG446| codons 1-99
PQITLWQRPLVTVRIGEQLIEALLDTGADDTVLEKINLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        P4S, V35T, T39A, E53ED, V118VI, I135V, S162A, K173IT, Q174QK, D177E, I178M, T200E, E203Q, Q207E, F214L, P243S, V245K, K275KQ, V276VI, K277KR, K281R, T286A, A288P, V292I, I293V, E297K, V317A, S322E, I326V, G335D, R356K, M357K, G359S, T369TA, A371AV, I375V, A376S, T386I, K390R, A400T, T403L  
>DG446| codons 1-426
PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAEMEKEGKISKIGPDNPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL
DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEMVI
YQYMDDLYVGSDLEIGQHREKIQELREHLLRWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQSIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIQIRQLCRLLRGAKPLTEIVPLTKEAE
LELAENREILKEPVHGAYYDPEKDLVAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKKRSA
HTNDVKQLAEVVQKVSTESIVIWGKIPKFRLPIQKETWETWWLEYWQATWIPEWEFVNTP
PLVKLW

References
Author Title Citation
Aghokeng, AF Evaluation of transmitted HIV drug resistance among recently-infected antenatal clinic attendees in four Central African countries. Antivir Ther, 2009