<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
CYN418 CYN418 Cameroon 2007 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13IV, I15IV, K20R, E35D, M36I, R41K, I62V, L63C, L89M  
>CYN418| codons 1-99
PQITLWQRPVVTVKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD
QVCIEICGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, D123E, S162A, K173A, Q174K, D177E, Q207E, P243A, V245Q, E248D, D250S, A272P, K275R, Q278H, T286A, E291D, V292I, I293V, E297A, L303M, D324DE, Q334H, G335D, F346H, M357R, R358K, G359S, Q367L, A371V, I375V, S379G, T386V, K390R, A400T E53EK, V111VG
>CYN418| codons 1-426
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPKNPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDGGDAYFSVPL
DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRAKNPEIVI
YQYMDDLYVGSDLEIGQHRTKIEELREHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQAIQLPDKSSWTVNDIQKLVGKLNWASQIYPGIRVKHLCKLLRGAKALTDIVPLTAEAE
LEMAENREILKEPVHGVYYDPSKELIAEIQKQGHDQWTYQIYQEPHKNLKTGKYARRKSA
HTNDVKLLTEVVQKVATEGIVIWGKVPKFRLPIQKETWETWWTEYWQATWIPEWEFVNTP
PLVKLW

References
Author Title Citation
Aghokeng, AF Evaluation of transmitted HIV drug resistance among recently-infected antenatal clinic attendees in four Central African countries. Antivir Ther, 2009