Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| V2000-22 | V2000-22P | Italy | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 255 |
| 2 | DDI | 48 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L | T215D | V60I, D123E, I135T |
| >V2000-22P| codons 30-226 KIKALVEICTELEKEGKISKIGPENPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWE VQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKEFRKYTAFTIPSTNNETPGIRYQYNVL PQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIGQHRTKIEELRQHL LRWGFDTPDKKHQKEPP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12A, I13V, I15V, L24F, N37D, D60E, Q61E, L63P |
| >V2000-22P| codons 1-99 PQITLWQRPLVAVKVGGQLKEALFDTGADDTVLEEMDLPGRWKPKMIGGIGGFIKVRQYE EIPIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Venturi, G | Antiretroviral resistance mutations in human immunodeficiency virus type 1 reverse transcriptase and protease from paired cerebrospinal fluid and plasma samples. | J Infect Dis, 2000 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |