Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA6007 | CA14915 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 157 |
| 2 | 3TC+AZT | 26 |
| 3 | 3TC+AZT+NFV | 48 |
| 4 | D4T+DDI+IDV | 89 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, L90M | N88D | L10I, I13V, Q18QH, N37D, K55KR, L63P, I66F, A71V, V77I |
| >CA14915| codons 1-99 PQITLWQRPIVTVKIGGHLKEALLDTGADDTVLEEMDLPGRWKPKLIGGIGGFIRVRQYD QIPIEFCGHKVIGTVLIGPTPVNIIGRDLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R | K64R, K122E, I135T, I178M, A272T, A288S, I293V, E297A |
| >CA14788| codons 1-300 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIRKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYTGIKVKQLCKLLRGTKSLTEVVPLTAEAE |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |