Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 044 | 044PR_RT | Brazil | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 22 |
| 2 | AZT+DDI+SQV | 43 |
| 3 | 3TC+AZT+IDV | 43 |
| 4 | D4T+DDI+RTV+SQV | 43 |
| 5 | DDI+RTV+SQV | 48 |
| 6 | AZT+DDI+EFV | 31 |
| 7 | DDI+IDV+RTV | 22 |
| 8 | D4T+DDI+LPV | 70 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, I84V, L90M | L10F, F53L, G73S | I3N, K14R, I15V, K20M, L63P, A71V, I72V, V77I, I85V, I93L |
| >044PR_RT| codons 1-99 PQNTLWQRPFVTIRVGGQLMEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGLVKVRQYD QIPIEICGHKVVSTVLIGPTPVNVVGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L210W, T215Y | K219R | E44D, V106I, V118I, K122E, I135T, S162C, T200A, E203D, H208Y, R211K, K223T |
| >044PR_RT| codons 1-233 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTELEKDGKISKIGPENPYNTPV FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSITVLDVGDAYFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPDIVI YQYMDDLYVGSDLEIGQHRAKIDELRQYLWKWGFYTPDRKHQTEPPFLWMGYE |
References
| Author | Title | Citation |
| Santos, AF | Characterization of a new circulating recombinant form comprising HIV-1 subtypes C and B in southern Brazil. | AIDS, 2006 |