<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
036 036PR_RT Brazil 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 AZT+DDI 4
2 AZT+DDC 22
3 3TC+AZT 91
4 3TC+D4T+NVP 17
5 Unknown 4
6 D4T+DDI+RTV+SQV 13
7 Unknown 87
8 3TC+AZT+RTV+SQV 30
9 Unknown 4
10 D4T+EFV+LPV 4

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I15V, M36I, N37K, R41N, H69K, L89M, I93L  
>036PR_RT| codons 1-99
PQITLWQRPLVTIKVGGQLKEALLDTGADDTVLEEIKLPGNWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, E36D, T39E, K122E, I135T, K173T, D177E, T200A, Q207E, R211K, F214L  
>036PR_RT| codons 1-218
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTDICEEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTQNPEIVI
YQYMDDLYVGSDLEIGQHRAKIEELREHLLKWGLTTPD

References
Author Title Citation
Santos, AF Characterization of a new circulating recombinant form comprising HIV-1 subtypes C and B in southern Brazil. AIDS, 2006