Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 205 | 205 | Brazil | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 4 |
| 2 | AZT+DDI | 8 |
| 3 | 3TC+AZT | 127 |
| 4 | D4T+DDI+NFV | 117 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39D, K43R, S48T, V60I, K122E, D123G, E138A, I142V, K173Q, R211K, V245Q, A272P, E291D, V292I, I293V, G335D, R356K, G359T, K366R, T377Q, K390R, E404D, V435A, L452M, V466I, S468T, D471E, H483Q, L484I, L491S, S519N, K530R, A534S, A554N |
| >205| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICDEMEREGKITKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNATPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRQQNPDIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVRQLTEAVQKIAQESIVIWGKTPKFRLPIQKETWEAWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAGAETFYVDGAANRETKMGKAGYVTDRGRQKIVTLTETTNQKTELQ AIQIALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSNGIRKVL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| K14R, I15V, G16E, K20R, M36I, N37K, P39S, R41N, H69K, I93L |
| >205| codons 1-99 PQITLWQRPLVTIRVEGQLREALLDTGADDTVLEEIKLSGNWKPKMIGGIGGFIKVRQYD QILIEICGKKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Santos, AF | Characterization of a new circulating recombinant form comprising HIV-1 subtypes C and B in southern Brazil. | AIDS, 2006 |
| Dumans, AT | Synonymous genetic polymorphisms within Brazilian human immunodeficiency virus Type 1 subtypes may influence mutational routes to drug resistance. | J Infect Dis, 2004 |