<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
157 MC157 Mozambique 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12TA, I15V, L19V, K20M, M36I, P39Q, R41K, R57RK, H69K, L89M, I93L  
>MC157| codons 1-99
PQITLWQRPLVAIKVGGQVMEALLDTGADDTVLEEINLQGKWKPKMIGGIGGFIKVKQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
      V179VD V35T, E36A, T39E, S48ST, K122E, A158AS, K173A, D177E, G196K, T200A, Q207QAEP, R211K, V245K, A272P, L279M, T286A, E291D, V292I, I293IV, E297A, V317VA  
>MC157| codons 1-320
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRAQNPEIDI
YQYMDDLYVGSDLEIKQHRAKIEELRPHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQMCKLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGAYYD

References
Author Title Citation
Bellocchi, MC Subtype analysis and mutations to antiviral drugs in HIV-1-infected patients from Mozambique before initiation of antiretroviral therapy: Results from the DREAM programme. J Med Virol, 2005