Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| RENA780 | RENA780 | Brazil | 2004 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+IDV | 200 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A | K43T | L10I, K14R, I15V, K20R, E35D, M36I, N37H, R41K, R57K, Q61D, L63P, L89M, I93IL |
| >RENA780| codons 1-99 PQITLWQRPIVTIRVGGQLREALLDTGADDTVLEDIHLPGKWTPKMIGGIGGFVKVKQYD DIPIEICGHKAIGTVLVGPTPANIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V35T, K122P, I135L, S162C, K173T, Q174K, I178L, T200A, Q207K, R211T, V245Q, E248D, A272P, T286A, V292I, I293V, P294T, E297A |
| >RENA780| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DPDFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRTKNPDLVI YQYVDDLYVGSDLEIGQHRAKIEELRKHLLTWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEIVTLTAEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGQG |
References
| Author | Title | Citation |
| Dumans, AT | Distinct resistance mutation and polymorphism acquisition in HIV-1 protease of subtypes B and F1 from children and adult patients under virological failure. | Infect Genet Evol, 2009 |