Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| RENA140 | RENA140 | Brazil | 2002 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 91 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, T215FY | K219E | E28K, V35T, K122Q, I135V, S162C, E169D, K173T, Q174K, I178L, T200A, I202V, Q207A, R211Q, V245Q, E248D, A272P, T286A, A288T, E291D, V292I, I293V, E297A, I329L |
| >RENA140| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTKEKIKALTEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DQDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRTKNPDLVI YQYVDDLYVGSDLEIGQHRAKVEELRAHLLQWGFYTPDEKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKTLTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAELQKQGQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | L10I, I13V, I15V, E35D, M36I, R41K, R57K, Q61D, L63C, K70R, I72T, L89M |
| >RENA140| codons 1-99 PQITLWQRPIVTVKVGGQLKEALLDTGADNTVLEDINLPGKWKPKMIGGIGGFIKVKQYD DICIEICGHRATGTVLVGPTPVNIIGRDMLTQIGCTLNF |
References
| Author | Title | Citation |
| Dumans, AT | Distinct resistance mutation and polymorphism acquisition in HIV-1 protease of subtypes B and F1 from children and adult patients under virological failure. | Infect Genet Evol, 2009 |