Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 75PR | 75PR | Brazil | 2002 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 104 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74I, L210W, T215F | K219W | P4S, V35T, T39M, K43Q, S162C, E169D, K173A, Q174K, I178L, I202V, Q207E, H208Y, R211K, K223Q, L228R |
| >75PR| codons 1-240 PISSIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICMELEQEGKISKIGPENPYNTPV FAIKKKNSTKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILDPFRAKNPDLVI YQYMDDLYVGSDLEIGQHRTKVEELREYLWKWGFFTPDWKHQQEPPFRWMGYELHPDKWT |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54A, V82T | K43T | L10I, K20R, E35D, M36I, R41K, R57K, D60E, Q61N, L63E, E65D, I72V, L89M, I93L |
| >75PR| codons 3-99 ITLWQRPIVTIKIGGQLREALLDTGADDTVLEDINLPGKWTPKMIVGIGGFAKVKQYENI EIDICGHKAVGTVLVGPTPTNIIGRNMLTQLGCTLNF |
References
| Author | Title | Citation |
| Dumans, AT | Distinct resistance mutation and polymorphism acquisition in HIV-1 protease of subtypes B and F1 from children and adult patients under virological failure. | Infect Genet Evol, 2009 |