Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 117PR | 117PR | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+IDV | 4 |
| 2 | 3TC+D4T+IDV | 65 |
| 3 | 3TC+D4T+RTV | 10 |
| 4 | D4T+DDI+LPV | 103 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103N | K20R, K122E, Q174H, D177N, Q197E, I202V | D256A |
| >117PR| codons 1-257 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKHNPNIVI YQYMDDLYVGSDLEIGEHRTKVEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNAI |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| E35D, M36I, P39Q, R41K, R57K, D60E, Q61D, I62V, L63P, L89M |
| >117PR| codons 1-99 PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEDINLQGKWKPKMIGGIGGFIKVKQYE DVPIEICGHKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Dumans, AT | Distinct resistance mutation and polymorphism acquisition in HIV-1 protease of subtypes B and F1 from children and adult patients under virological failure. | Infect Genet Evol, 2009 |