Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| RES165_03 | RES165_03 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDC+SQV | 126 |
| 2 | 3TC+D4T+EFV | 169 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V | L10V, I15V, E35D, M36I, R41K, R57K, Q61D, H69Y, I72K, T74S |
| >RES165_03| codons 1-99 PQITLWQRPVVTIKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD DILIEICGYKAKGSVLVGPTPVNVIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184I | K20R, V35I, K43E, E44A, L228F |
| >RES165_03| codons 1-260 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALIEICTELEEAGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYIDDLYVGSDLEIGQHRTKIEELRQHLLRWGFTTPDKKHQKEPPFFWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKL |
References
| Author | Title | Citation |
| Dumans, AT | Distinct resistance mutation and polymorphism acquisition in HIV-1 protease of subtypes B and F1 from children and adult patients under virological failure. | Infect Genet Evol, 2009 |