Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| RES303_03 | RES303_03 | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDC+RTV | 157 |
| 2 | Unknown | 4 |
| 3 | 3TC+D4T+NVP | 117 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A | L10I, K14R, I15V, L19I, K20R, E35D, M36I, R41K, R57K, Q61N, T74A, L89M |
| >RES303_03| codons 1-99 PQITLWQRPIVTIRVGGQIREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFVKVKQYD NILIEICGHKAIGAVLVGPTPANIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, M184V | T215V, K219Q | G190A | K101H | E28G, K122E, S162C, K166R, E169D, Q197K, T200A |
| >RES303_03| codons 1-256 PISPIETVPVKLKPGMDGPKVKQWPLTGEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLHKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTRILDPFRKQNPDIVI YQYVDDLYVASDLEIGKHRAKIEELRQHLLRWGFVTPDQKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVND |
References
| Author | Title | Citation |
| Dumans, AT | Distinct resistance mutation and polymorphism acquisition in HIV-1 protease of subtypes B and F1 from children and adult patients under virological failure. | Infect Genet Evol, 2009 |