Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| RES299_03 | RES299_03 | Brazil | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+DDI | 35 |
| 2 | 3TC+AZT+NFV | 104 |
| 3 | D4T+DDI+NFV | 35 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V, L210W, T215Y | K219E | K103S, G190A | K101R, K122E, D123N, I135T, V245K |
| >RES299_03| codons 1-252 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLRKSKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVASDLEIGQHRTKIEELRQHLWRWGFYTPDEKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSW |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| N88S | L10V, I15V, K20T, E35D, M36I, R41K, K45R, R57K, Q61N |
| >RES299_03| codons 1-99 PQITLWQRPVVTIKVGGQLTEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD NILIEICGHKAIGTVLVGPTPVNIIGRSLLTQIGCTLNF |
References
| Author | Title | Citation |
| Dumans, AT | Distinct resistance mutation and polymorphism acquisition in HIV-1 protease of subtypes B and F1 from children and adult patients under virological failure. | Infect Genet Evol, 2009 |