Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 108PR | 108PR | Brazil | 2003 | HIV1 | F | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 4 |
| 2 | 3TC+D4T+NFV | 22 |
| 3 | Unknown | 104 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | N88D | I15V, K20T, E35D, M36I, N37D, R41K, R57K, Q61N, A71V, V77I, I93L |
| >108PR| codons 1-99 PQITLWQRPLVTIKVGGQLTEALLDTGADNTVLEDIDLPGKWKPKMIGGIGGFIKVKQYD NILIEICGHKVIGTVLIGPTPVNIIGRDLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V75M, M184V | K122E, D123E, D177E, Q207E, R211K, A272P, K281R, E297K, K311R, P313T, G333E |
| >108PR| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLMDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYVDDLYVGSDLEIGQHRTKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGTKALTEVIPLTKEAE LELAENREILRETVHGVYYDPSKDLIAEIQKQEQG |
References
| Author | Title | Citation |
| Dumans, AT | Distinct resistance mutation and polymorphism acquisition in HIV-1 protease of subtypes B and F1 from children and adult patients under virological failure. | Infect Genet Evol, 2009 |