<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
pt1198 5uPPZWnXL6 Germany 2004 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I13V, K14R, K20I, E35Q, M36I, N37D, R41K, R57K, C67E, H69K, V82I, L89M, I93IL  
>5uPPZWnXL6| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEQIDLPGKWKPKMIGGIGGFIKVKQYD
QILIEIEGKKAIGTVLVGPTPINIIGRNMLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V21I, V35T, T39R, E40ED, V60I, K122KE, D123E, K173T, Q174A, D177E, I178M, T200A, Q207S, R211K, V245Q, A272P, K275R, Q278H, T286A, E291D, I293V, P294T, E297A, L303M, V314M, D324E, Q334H, G335D  
>5uPPZWnXL6| codons 1-339
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICRDMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTANPEMVI
YQYMDDLYVGSDLEIGQHRAKIEELRSHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKHLCKLLRGAKALTDVVTLTAEAE
LEMAENREILKEPMHGVYYDPSKELIAEIQKQGHDQWTY

References
Author Title Citation
Vercauteren, J Transmission of drug-resistant HIV-1 is stabilizing in Europe. J Infect Dis, 2009