Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5719 | CA14247 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+D4T+NFV | 119 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90LM | T12S, L19I, K20I, D60DE, I62V, L63X, I64V, H69Q, T74A, V77I, I93IL |
| >CA14247| codons 1-99 PQITLWQRPLVSIKIGGQIIEALLDTGADDTVLEEMNLPGRWKPKIIGGIGGFIKVRQYE QVXVEICGQKAIGAVLIGPTPVNIIGRNLMTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K102Q, K122KE, D123E, I135T, E138A, T139IM, I142V, S162C, D177E, V179I, T200I, V245M |
| >CA14138| codons 1-257 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKQKKSVTVLDVGDAYFSVPL DEEFRKYTAFTIPSTNNAIPGVRYQYNVLPQGWKGSPAIFQCSMTKILEPFRKQNPEIII YQYVDDLYVGSDLEIGQHRIKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKDSWTVNDI |
References
| Author | Title | Citation |
| Gonzales, MJ | HIV-1 reverse transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a Northern California clinic-based population. | J Infect Dis, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |