Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA5718 | CA14246 | U.S. | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 52 |
| 2 | 3TC+AZT+IDV | 35 |
| 3 | D4T+DDI+NFV | 71 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32I, I54IV, V82A, L90M | L10LI, L19I, E35D, M36MI, M46X, L63P, I64V, I66IF, A71V |
| >CA14246| codons 1-99 PQITLWQRPIVTIKIGGQIKEALLDTGADDTILEDINLPGRWKPKXIGGIGGFVKVRQYD QIPVEFCGHKVIGTVLVGPTPANIIGRNLMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| T69S_SS, T215Y | A62V, D67E | K122E, I135IV, I142IV, D177E, L228H, A272AG, T286A, A288AG | N265NS, E291EV |
| >CA14137| codons 1-296 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FVIKKKESSKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEIVI YQYMDDLYVGSDLEIGQHRTKIEELRQHLLRWGFYTPDKKHQKEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLSWASQIYGGIKVKQLCKLLRGAKGLTVVIPLT |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |