<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
P1273 P1273.1 Spain 2006 HIV1 F Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    L10V, I13V, I15V, E35D, M36I, R41K, R57K, D60E, Q61D, V77I, L89M  
>P1273.1| codons 1-99
PQITLWQRPVVTVKVGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYE
DILIEICGHKAIGTVLIGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        S48E, D123E, I135T, K166KR, I178M, D192N, T200A, R211K  
>P1273.1| codons 1-214
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKIEKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DKEFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPDMVI
YQYMDDLYVGSNLEIGQHRAKIEELRQHLLKWGF

References
Author Title Citation
Cuevas, MT HIV-1 transmission cluster with T215D revertant mutation among newly diagnosed patients from the Basque Country, Spain. JAIDS, 2009