Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 78 | 03p78-2 | Germany | 2003 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 163 |
| 2 | DDI | 36 |
| 3 | DDI+SQV | 5 |
| 4 | 3TC+DDI+SQV | 9 |
| 5 | 3TC+D4T+SQV | 17 |
| 6 | 3TC+D4T+RTV | 24 |
| 7 | D4T+RTV | 22 |
| 8 | D4T+RTV+SQV | 59 |
| 9 | ABC+DDI+EFV | 182 |
| 10 | ABC+DDI+TDF | 66 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82VA | L33F | L10V, I13V, K14R, G16A, M36I, N37D, R57K, L63E, I64IV, E65D, C67CY, V77VI |
| >03p78-2| codons 1-99 PQITLWQRPVVTVRIAGQLKEALLDTGADDTVFEEIDLPGRWKPKMIGGIGGFIKVKQYD QIEVDIYGHKAIGTVLIGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, L74V, Y115YF, M184MV, L210W, T215Y | K219N | L100LI, K103N, V106VA | F227FL | V35M, T39A, K43E, V90VI, A98S, V118I, K122E, I135T, G196E, T200A, I202V, H221HY, A272P, K275KR, I293V, K311R, Q334E |
| >03p78-2| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICAELEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKVVDFRELNKRTQDFWEIQLGIPHPSGIKKNKSATVLDVGDAFFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIEQHRAKVEELRQHLWRWGFYTPDNKYQKEPPLLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGTKALTEVVPLTEEAE LELAENREILREPVHGVYYDPSKDLIAEIQKQGEG |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |