Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 78 | 02p78-1 | Germany | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 163 |
| 2 | DDI | 36 |
| 3 | DDI+SQV | 5 |
| 4 | 3TC+DDI+SQV | 9 |
| 5 | 3TC+D4T+SQV | 17 |
| 6 | 3TC+D4T+RTV | 24 |
| 7 | D4T+RTV | 22 |
| 8 | D4T+RTV+SQV | 59 |
| 9 | ABC+DDI+EFV | 175 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, L74LV, Y115YF, M184MV, L210W | K219KR | L100LI, K103N, V106VA | F227FL | V35M, T39A, K43E, A98S, V118I, K122E, I135T, G196E, T200A, I202V, R211RK, H221HY, A272P, K275KR, I293V, Q330P, Q334E | E328EQ |
| >02p78-1| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICAELEEEGKISKIGPENPYNTPV FAIKKKNSTKWRKVVDFRELNKRTQDFWEVQLGIPHPSGIKKNKSATVLDVGDAFFSIPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVI YQYVDDLYVGSDLEIEQHRAKVEELRQHLWKWGFTTPDRKYQKEPPLLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAQIPKQGEG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82A | L33F | L10V, I13V, K14R, G16A, M36I, N37D, R57K, L63E, I64IV, E65D, V77VI |
| >02p78-1| codons 1-99 PQITLWQRPVVTVRIAGQLKEALLDTGADDTVFEEIDLPGRWKPKMIGGIGGFIKVKQYD QIEVDICGHKAIGTVLIGPTPANIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rosen-Zvi, M | Selecting anti-HIV therapies based on a variety of genomic and clinical factors. | Bioinformatics, 2008 |